39 research outputs found

    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

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    PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    COVID-19 Pandemic and Ophthalmologists Response

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    Egrilmez, Sait/0000-0002-6971-527X; Bozkurt, Banu/0000-0002-9847-3521; Sengor, Tomris/0000-0002-9436-5582WOS:000544811700014PubMed: 32631036[No Abstract Available

    The COVID-19 Pandemic: Clinical Information for Ophthalmologists

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    Egrilmez, Sait/0000-0002-6971-527X; Bozkurt, Banu/0000-0002-9847-3521WOS:000530626600002PubMed: 32366061[No Abstract Available

    A case of mediastinal lymphangioma: endosonographic appearance

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    Mediastinal lymphangioma is a rare, benign disease characterized by an abnormal proliferation of lymphatic vessels. Although a definitive diagnosis can be best made by surgical resection, computed tomography (CT) and magnetic resonance imaging (MRI) can be used as radiological methods to diagnose a pulmonary lymphangioma preoperatively. Endoscopic ultrasonography is a new method for visualizing pathological changes in the mediastum and may be used for preoperative diagnosis of a pulmonary lymphangioma, which is a rare example of a mediastinal disease

    Arterial Mycotic Aneurysm Rupture of Two Kidney Cadaveric Renal Transplantation Recipients Secondary to Enterococci and Candida

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    Although vascular complications due to the arterial anastomosis are rare in transplant patients, infectious vascular complications around the anastomosis site that carry a risk of rupture can cause significant mortality and morbidity. Signs and symptoms of any infectious process can be masked in patients taking more potent immunosuppressants at the early period after transplantation. Staphylococcus aureus, gram-negative bacilli, and fungi such as Candida albicans can especially produce serious complications. We present two renal transplant patients with an arterial anastomosis aneurysm leading to rupture. Early diagnosis may be life saving due to the silent and insidious presentation of arterial mycotic aneurysms and their high mortality and morbidity rates.Böbrek transplant hastalarında arteryel anastomoz hatlarından kaynaklanan komplikasyonlar son zamanlarda oldukça nadir olsa da, anlamlı mortalite ve morbiditeye sebep olabilecek enfeksiyöz patolojiler hala görülebilmektedir. Transplant sonrası erken dönemde kullanılan güçlü immünsupresif ilaçlar, klinik bulgu ve semptomları maskeleyebilmektedir. Özellikle Staphylococcus aureus, gram negatif basiller ve Candida albicans gibi mantarlar tehlikeli komplikasyonlar oluşturabilirler. Biz burada arteryel anastomoz hattı enfeksiyonuna sekonder rüptür ile komplike olmuş iki transplant hastasını tartışacağız. Yüksek mortalite ve morbidite riski taşımaları sebebiyle, sessiz ve sinsi gidişatlı arteryel mikotik anevrizmaların erken saptanması, hayat kurtarıcı olabilir

    Carbon based nanomaterials for high performance optoelectrochemical systems

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    Carbon nanotubes (CNT) and graphene are two significant carbon based nanomaterials which have extraordinary physicochemical properties, used in diverse fields of research. Recently, some actual studies were made to associate these carbon nanomaterials to produce CNT-graphene hybrid with synergic effects of graphene and CNTs. Addressed herein, EDOT-modified reduced graphene oxide (rGO), functionalized multiwalled carbon nanotube (f-MWCNT) and hybrid material (rGO-f-MWCNT) have been prepared. Then, PEDOT-modified composite films were synthesized via electrochemical polymerization to examine enhancing electrochemical properties of PEDOT and characterized by SEM, AFM analysis. As a conclusive finding, an improved stability, charge density, electrochromic switching kinetics and optical contrast of polymer composite films were observed on presence of nanocarbon materials in comparison to the control PEDOT film due to facile ion transport, high surface area
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